Povidone

Pyrrolidone series products include NMP, NOP, NEP, NVP, PVP K,PVP I,2-Pyrrolidone etc.

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Polyvinylpyrrolidone (Povidone) - Covers your daily life

In synthetic polymers, PVP is soluble in water and soluble in most organic solvents. It is very low in toxicity and physiologically compatible, especially in medicine, food and cosmetics.And other areas closely related to people's health.


Manlice - Povidone acts on Medicine & Health

PVP has excellent physiological inertia, does not participate in human metabolism, and has excellent biocompatibility, and does not form any irritation to skin, mucous membranes, eyes and the like. Pharmaceutical grade PVP is one of the three major medicinal excipients advocated by the international community. It can be used as a binder for tablets and granules, as a co-solvent for injections, as a glidant for capsules, as an antidote for eye drops, as a deterrent, and for lubrication. Agents and coating film formers, dispersing agents for liquid preparations and stabilizers for enzymes and heat sensitive drugs can also be used as cryopreservatives. Used in contact lenses to increase their hydrophilicity and lubricity.
From a biological point of view, the molecular structure of PVP is similar to that of a simple protein model, even its water-soluble ability to bind certain small molecules and ammonium sulfate, which is a precipitant for certain proteins. Properties such as precipitation of trichloroacetic acid, tannic acid and phenols are also compatible with proteins. So that PVP is widely used as an excipient for pharmaceutical preparations, the specific application is as follows:

  • As a binder for the preparation.
  • Coprecipitant.
  • As a cosolvent in the injection or a crystallization inhibitor.
  • Coating or film former.
  • Controlled release of slow-release and sustained-release drugs can prolong the action time of the drug.
  • Artificial vitreous and corneal.
  • Surgical banding.
  • PVP iodine disinfectant.

In addition, PVP can also be used as a coloring agent and X-ray contrast agent; it can be used in various dosage forms such as tablets, granules and water, and has the functions of detoxification, hemostasis, increasing dissolution concentration, preventing peritoneal adhesion, and promoting blood sedimentation.

Green food comes from the important role Povidone plays in food processing

PVP itself does not cause cancer, has good food safety, can form complexes with specific polyphenol compounds (such as tannins), and is mainly used as food clarifying agent and stabilizer for beer, juice, wine, etc. in food processing. PVP can form complexes with specific polyphenolic compounds such as tannins, which provide clarification and anti-coagulation in fruit juice beverages.
Added 0.01% ~ 0.02% soluble PVP in the fermenter to effectively reduce the freezing point. The use of PVP in the production of wine and vinegar can also play the same role. Cross-linked PVP is widely used in beer and tea beverages. The polyphenols in beer can combine with the protein in beer to form a tannin macromolecule, which will seriously affect the flavor of beer and shorten its shelf life.
Cross-linked polyvinylpyrrolidone (PVPP) can be combined with tannic acid and anthocyanins in beer to clarify beer, improve beer storage stability and extend shelf life. In the tea beverage, the use of PVPP can appropriately reduce the content of tea polyphenols, and PVPP does not remain in the tea beverage, and can be reused, thereby greatly reducing the cost.

  • Daily Cosmetics

    In the consumption structure of PVP, the cosmetics industry in developed countries accounts for 30% to 50%, and China accounts for 70% to 80%. Since PVP has extremely low toxicity and physiological inertia, it has no irritation to the skin and eyes, and has a long-term use record in the medical field, so it is safe for use in cosmetics and the like. In daily cosmetics, PVP and copolymer have good dispersibility and film formability. PVP has a protective colloid effect in the emulsion. It can be used in fat and non-fat pastes, as a setting liquid, hair spray and rubber ect.

  • Detergent

    PVP has anti-soil re-precipitation performance, can be used to prepare transparent liquid or heavy dirt detergent. Adding PVP to detergent has good anti-color conversion effect, and can enhance the cleaning ability. It can prevent synthetic detergent when washing fabric. Skin irritation, especially for synthetic fibers, is more pronounced than carboxymethyl cellulose (CMC) detergents. PVP can be formulated with borax as an active ingredient in phenol-containing disinfectant formulations. The detergent compounded with PVP and hydrogen peroxide solid has the function of bleaching and killing bacteria.

  • Textile

    PVP has a good affinity with many organic dyes. It can be combined with hydrophobic synthetic fibers such as polyacrylonitrile, ester, nylon and fibrous materials to improve dyeing power and hydrophilicity.reported that after the graft copolymerization of PVP and nylon, the fabric produced improved wet wrinkle resistance and moisture resistance.

  • Paints & pigments

    PVP coated paints and coatings are transparent to the film without affecting the original color, improving the gloss and dispersibility of the paint and pigment, improving the thermal stability and improving the dispersibility of the ink and ink. PVP for surface treatment of organic pigments is generally PVP-K30, PVP-K90 or PVP VA64.

Other aspects

PVP can be used as a gelling agent for tertiary oil recovery to improve the oil recovery rate of oil fields. The additive as a photosensitive material contributes to lowering the degree of latex and enhancing the coverage of the developed image. Used as a thickener, dispersion stabilizer, and adhesion modifier in polymer polymerization. Used as a dispersant in the paper industry as a cocatalyst in the propylene amine gasification reaction. The application of PVP in separation membranes, photocurable resins, laser discs, drag coatings, building materials, steel making and electroplating is also on the rise.