Polyvinylpyrrolidone (Povidone) - Covers your daily life

Manlice - Povidone acts on Medicine & Health

PVP has excellent physiological inertia, does not participate in human metabolism, and has excellent biocompatibility, and does not form any irritation to skin, mucous membranes, eyes and the like. Pharmaceutical grade PVP is one of the three major medicinal excipients advocated by the international community. It can be used as a binder for tablets and granules, as a co-solvent for injections, as a glidant for capsules, as an antidote for eye drops, as a deterrent, and for lubrication. Agents and coating film formers, dispersing agents for liquid preparations and stabilizers for enzymes and heat sensitive drugs can also be used as cryopreservatives. Used in contact lenses to increase their hydrophilicity and lubricity.
From a biological point of view, the molecular structure of PVP is similar to that of a simple protein model, even its water-soluble ability to bind certain small molecules and ammonium sulfate, which is a precipitant for certain proteins. Properties such as precipitation of trichloroacetic acid, tannic acid and phenols are also compatible with proteins. So that PVP is widely used as an excipient for pharmaceutical preparations, the specific application is as follows:

• As a binder for the preparation.
• Coprecipitant.
• As a cosolvent in the injection or a crystallization inhibitor.
• Coating or film former.
• Controlled release of slow-release and sustained-release drugs can prolong the action time of the drug.
• Artificial vitreous and corneal.
• Surgical banding.
• PVP iodine disinfectant.

In addition, PVP can also be used as a coloring agent and X-ray contrast agent; it can be used in various dosage forms such as tablets, granules and water, and has the functions of detoxification, hemostasis, increasing dissolution concentration, preventing peritoneal adhesion, and promoting blood sedimentation.

Green food comes from the important role Povidone plays in food processing

PVP itself does not cause cancer, has good food safety, can form complexes with specific polyphenol compounds (such as tannins), and is mainly used as food clarifying agent and stabilizer for beer, juice, wine, etc. in food processing. PVP can form complexes with specific polyphenolic compounds such as tannins, which provide clarification and anti-coagulation in fruit juice beverages.
Added 0.01% ~ 0.02% soluble PVP in the fermenter to effectively reduce the freezing point. The use of PVP in the production of wine and vinegar can also play the same role. Cross-linked PVP is widely used in beer and tea beverages. The polyphenols in beer can combine with the protein in beer to form a tannin macromolecule, which will seriously affect the flavor of beer and shorten its shelf life.
Cross-linked polyvinylpyrrolidone (PVPP) can be combined with tannic acid and anthocyanins in beer to clarify beer, improve beer storage stability and extend shelf life. In the tea beverage, the use of PVPP can appropriately reduce the content of tea polyphenols, and PVPP does not remain in the tea beverage, and can be reused, thereby greatly reducing the cost.